The authors offer an excellent reference on amyotrophic lateral sclerosis (ALS) with advances and perspectives on neuro-nanomedicine. Medical image professionals, graduate student and medical doctors could benefit from this book.

ALS is also known as Lou Gehrig disease. The complexity of diagnostic modalities for neurodegenerative disorders like ALS and Alzheimer’s, based on neurotoxicity, has been greatly improved through the advances of medical imaging modalities. Readers will find electrophysiological studies in combination with MRI imaging modalities. Furthermore, there is a broader discussion on diagnostic medical imaging for ALS that includes the increasing role of magnetic multimodal contrast agents for enhanced nano-based optical imaging—e.g., SECARS (surface enhanced coherent anti-Stokes Raman scattering microscopy) and micro-emulsion methodology for effective drug delivery.

Future challenges are addressed within the context of cell replacement therapies, like stem-cell therapies in connection with multi-modal medical imaging technologies.

Review by Axel Mainzer Koenig, CEO, 21st Century Data Analysis, Portland, Ore., USA. 

The opinions expressed in the book review section are those of the reviewer and do not necessarily reflect those of OPN or OSA.