Probing the Eye More Deeply: Adaptive Optics Multiphoton Microscopy

Juan M. Bueno

The integration of adaptive optics techniques into ophthalmic imaging devices has improved the diagnosis and treatment of eye diseases. The coupling of adaptive optics with multiphoton microscopy may help extend the reach of ophthalmic imaging to greater depths within the cornea and retina.

 

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Detection and diagnosis of ocular pathologies and genetic anomalies require accurate visualization of the structures of the eye. However, the different layers of the cornea and the retina are transparent and often hard to image under natural conditions with clinical devices. Several imaging modalities improve a clinician’s ability to view the cornea and retina, including specular microscopy and systems that integrate adaptive optics (AO) techniques.

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