Light-Scattering Method Measures Cell Nuclei

Yvonne Carts-Powell

Researchers demonstrated a light-scattering technique called angle-resolved low-coherence interferometry (a/LCI) that provides a better method for measuring cell nuclei.

 

Scatterings imageThe nucleus of a cell blows up like a balloon as the salinity of the surrounding fluid decreases.

Measuring changes in the shape of cell nuclei can provide clues to processes within the cell and a possible means for detecting precancerous cells. But it can also be a difficult process. Usually, measuring the dimensions involves labeling a nucleus, imaging it with fluorescence microscopy, and then analyzing the image.

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